Rabbit Anti-Kir2.2/FITC Conjugated antibody

Home > Product > Antibody > Rabbit Anti-Kir2.2/FITC Conjugated antibody

ATP sensitive inward rectifier potassium channel 12; ATP-sensitive inward rectifier potassium channel 12; hIRK; Human high conductance inward rectifier potassium channel alpha; Inward rectifier K; Inward rectifier K(+) channel Kir2.2; Inward rectifi

Cat:

SL17068R-FITC

Species Reactivity：

Mouse,Rat,(predicted: Human,)

Immunogen：

KLH conjugated synthetic peptide derived from human Kir2.2

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

49kDa

prev next

Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
Feedback Wall

background:
Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium and cesium.

Subcellular Location:
Membrane.

Similarity:
Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
KCNJ12 subfamily.

Database links:

Entrez Gene: 403760 Dog

Entrez Gene: 100131509 Human

Entrez Gene: 10058070 Human

Entrez Gene: 3768 Human

Entrez Gene: 16515 Mouse

Entrez Gene: 117052 Rat

Omim: 602323 Human

SwissProt: Q4TZY1 Cow

SwissProt: Q14500 Human

SwissProt: P52187 Mouse

SwissProt: P52188 Rat

Unigene: 200629 Human

Unigene: 4970 Mouse

Unigene: 10406 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Product Feedback Wall