Rabbit Anti-LARP4B/LARP5/FITC Conjugated antibody

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A630096F19; AI256361; D13Wsu64e; KIAA0217; La ribonucleoprotein domain family member 4B; La ribonucleoprotein domain family member 5; La-related protein 4B; La-related protein 5; LAR4B_HUMAN; Larp4b; LARP5; MGC78318.

Cat:

SL17104R-FITC

Species Reactivity：

Human,Mouse,(predicted: Rat,)

Immunogen：

KLH conjugated synthetic peptide derived from human LARP4B/LARP5

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

81kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
This gene encodes a member of an evolutionarily conserved protein family implicated in RNA metabolism and translation. Members of this family are characterized by the presence of an La motif, which is often located adjacent to one or more RNA recognition motifs (RRM). Together, the two motifs constitute the functional region of the protein and enable its interaction with the RNA substrate. This protein family is divided into five sub-families: the genuine La proteins and four La-related protein (LARP) sub-families. The protein encoded by this gene belongs to LARP sub-family 4. It is a cytoplasmic protein that may play a stimulatory role in translation. [provided by RefSeq, Oct 2012]

Function:
Stimulates mRNA translation.

Subunit:
Interacts with PABPC1 and GNB2L1. Associates with polysomes via the 40S ribosomal subunit.

Subcellular Location:
Cytoplasm, cytosol

Similarity:
Contains 1 HTH La-type RNA-binding domain.
Contains 1 RRM (RNA recognition motif) domain.

Database links:

Entrez Gene: 23185 Human

SwissProt: Q92615 Human

Unigene: 631814 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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