Rabbit Anti-JAM2/FITC Conjugated antibody

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Junctional Adhesion Molecule 2; C21orf43; CD 322; CD322; CD322 antigen; JAM 2; JAM B; JAM IT/VE JAM; JAM, vascular endothelial; JAM-2; JAM-B; JAM2; JAM2_HUMAN; JAMB; Jcam2; Junction adhesion molecule 2; Junction adhesion molecule B; Juncti

Cat:

SL17213R-FITC

Species Reactivity：

Mouse,Rat,(predicted: Cow,Rabbit,Chimpanzee,Macaque Monkey, Gorilla, Orangutan)

Immunogen：

KLH conjugated synthetic peptide derived from human JAM2

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

48kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
This gene belongs to the immunoglobulin superfamily, and the junctional adhesion molecule (JAM) family. The protein encoded by this gene is a type I membrane protein that is localized at the tight junctions of both epithelial and endothelial cells. It acts as an adhesive ligand for interacting with a variety of immune cell types, and may play a role in lymphocyte homing to secondary lymphoid organs. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2012]

Function:
May play a role in the processes of lymphocyte homing to secondary lymphoid organs.

Subcellular Location:
Cell junction > tight junction. Cell membrane. Localized at tight junctions of both epithelial and endothelial cells.

Tissue Specificity:
Highest expression in the heart, placenta, lung, foreskin and lymph node. Prominently expressed on high endothelial venules, also present on the endothelia of other vessels. Localized to the intercellular boundaries of high endothelial cells.

Similarity:
Belongs to the immunoglobulin superfamily.
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
Contains 1 Ig-like SLVtype (immunoglobulin-like) domain.

Database links:

Entrez Gene: 538846 Cow

Entrez Gene: 58494 Human

Entrez Gene: 67374 Mouse

Entrez Gene: 619374 Rat

Omim: 606870 Human

SwissProt: P57087 Human

SwissProt: Q9JI59 Mouse

Unigene: 517227 Human

Unigene: 41758 Mouse

Unigene: 6473 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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