Rabbit Anti-SC11A/FITC Conjugated antibody

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1810012E07Rik; Endopeptidase SP18; Microsomal signal peptidase 18 kDa subunit; SC11A_HUMAN; SEC11 homolog A (S. cerevisiae); SEC11 homolog A; SEC11-like protein 1; SEC11A; SEC11L1; sid2895; Signal peptidase complex (18kD); Signal peptidase comp

Cat:

SL17254R-FITC

Species Reactivity：

Human,(predicted: Mouse,Rat,Dog,Cow,Rabbit,Zebrafish,Sheep,Orangutan)

Immunogen：

KLH conjugated synthetic peptide derived from human SC11A

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

21kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
This gene encodes a member of the peptidase S26B family. The encoded protein is an 18kDa subunit of the signal peptidase complex and has been linked to cell migration and invasion, gastric cancer and lymph node metastasis. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 8. [provided by RefSeq, Dec 2012]

Function:
Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum.

Subcellular Location:
Microsome membrane. Endoplasmic reticulum membrane.

Similarity:
Belongs to the peptidase S26B family.

Database links:

Entrez Gene: 23478 Human

Entrez Gene: 56529 Mouse

Entrez Gene: 65166 Rat

SwissProt: P67812 Human

SwissProt: Q9R0P6 Mouse

SwissProt: P42667 Rat

Unigene: 9534 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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