Home > Product > Antibody > Rabbit Anti-SCARF2/FITC Conjugated antibody
NSR1; Scarf2; Scavenger receptor class F member 2; Scavenger receptor expressed by endothelial cells 2 protein; SREC-II; SREC2; SREC2_HUMAN; SRECRP-1; SREPCR.
Cat:
SL17273R-FITC
Species Reactivity:
Human,(predicted: Mouse,Rat,Dog,Pig,Cow,Horse,)
Immunogen:
KLH conjugated synthetic peptide derived from human SCARF2
Format:
Lyophilized or Liquid
Storage instructions:
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant
Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
Calculated MW:
88kDa
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Unit:
Price: $
Product PDFs
Datasheet:


background:
The protein encoded by this gene is similar to SCARF1/SRESLCI, a scavenger receptor protein that mediates the binding and degradation of acetylated low density lipoprotein (Ac-LDL). This protein has only little activity of internalizing modified low density lipoproteins (LDL), but it can interact with SCARF1 through its extracellular domain. The association of this protein with SCARF1 is suppressed by the presence of scavenger ligands. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

Function:
Probable adhesion protein, which mediates homophilic and heterophilic interactions. In contrast to SCARF1, it poorly mediates the binding and degradation of acetylated low density lipoprotein (Ac-LDL).

Subcellular Location:
Membrane.

Tissue Specificity:
Predominantly expressed in endothelial cells. Expressed in heart, placenta, lung, kidney, spleen, small intestine and ovary.

Similarity:
Contains 7 EGF-like domains.

Database links:

Entrez Gene: 91179 Human

Entrez Gene: 24824 Mouse

Omim: 613619 Human

SwissProt: Q96GP6 Human

SwissProt: P59222 Mouse

Unigene: 474251 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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