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Rabbit Anti-SGK196/FITC Conjugated antibody
background:
This gene encodes a protein that may be involved in the presentation of the laminin-binding O-linked carbohydrate chain of alpha-dystroglycan (a-DG), which forms transmembrane linkages between the extracellular matrix and the exoskeleton. Some pathogens use this O-linked carbohydrate unit for host entry. Loss of function compound heterozygous mutations in this gene were found in a human patient affected by the Walker-Warburg syndrome (WWS) phenotype. Mice lacking this gene contain misplaced neurons (heterotopia) in some regions of the brain, possibly from defects in neuronal migration. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2013]
Function:
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. STKL subfamily.
Subcellular Location:
Cell Membrane
Database links:
Entrez Gene: 84197 Human
Entrez Gene: 306549 Rat
Omim: 615247 Human
SwissProt: Q9H5K3 Human
SwissProt: Q3TUA9 Mouse
SwissProt: Q4V8A9 Rat
Unigene: 491646 Human
Unigene: 39247 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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