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Rabbit Anti-TRPV2/FITC Conjugated antibody
background:
Calcium-permeable, non-selective cation channel with an outward rectification. Seems to be regulated, at least in part, by IGF-I, PDGF and neuropeptide head activator. May transduce physical stimuli in mast cells. Activated by temperatures higher than 52 degrees Celsius; is not activated by vanilloids and acidic pH.
Function:
Calcium-permeable, non-selective cation channel with an outward rectification. Seems to be regulated, at least in part, by IGF-I, PDGF and neuropeptide head activator. May transduce physical stimuli in mast cells. Activated by temperatures higher than 52 degrees Celsius; is not activated by vanilloids and acidic pH.
Subunit:
Homotetramer.
Subcellular Location:
Cell membrane; Multi-pass membrane protein. Cytoplasm. Melanosome.
Post-translational modifications:
N-glycosylated.
Phosphorylated by PKA.
Similarity:
Belongs to the transient receptor (TC 1.A.4) family. TrpV subfamily. TRPV2 sub-subfamily.
Contains 6 ANK repeats.
Database links:
Entrez Gene: 51393 Human
Omim: 606676 Human
SwissProt: Q9Y5S1 Human
Unigene: 279746 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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