Rabbit Anti-HNRPUL1/FITC Conjugated antibody

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Adenovirus early region 1B associated protein 5; Adenovirus early region 1B-associated protein 5; E130317O14Rik; E1B 55 kDa associated protein 5; E1B AP5; E1B-55 kDa-associated protein 5; E1B-AP5; E1BAP5; fb53d10; fk45c03; FLJ12944; Heterogeneo

Cat:

SL17347R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Cow,Horse,Cat,)

Immunogen：

KLH conjugated synthetic peptide derived from human HNRPUL1

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

96kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
This gene encodes a nuclear RNA-binding protein of the heterogeneous nuclear ribonucleoprotein (hnRNP) family. This protein binds specifically to adenovirus E1B-55kDa oncoprotein. It may play an important role in nucleocytoplasmic RNA transport, and its function is modulated by E1B-55kDa in adenovirus-infected cells. Two transcript variants encoding different isoforms have been found for this gene. Additional variants have also been found, but their full-length natures have not been determined. [provided by RefSeq, Jul 2008]

Function:
Acts as a basic transcriptional regulator. Represses basic transcription driven by several virus and cellular promoters. When associated with BRD7, activates transcription of glucocorticoid-responsive promoter in the absence of ligand-stimulation. Plays also a role in mRNA processing and transport. Binds avidly to poly(G) and poly(C) RNA homopolymers in vitro.

Subcellular Location:
Nucleus.

Post-translational modifications:
Methylated.

Similarity:
Contains 1 B30.2/SPRY domain.
Contains 1 SAP domain.

Database links:

Entrez Gene: 11100 Human

Entrez Gene: 232989 Mouse

Entrez Gene: 361522 Rat

Omim: 605800 Human

SwissProt: Q9BUJ2 Human

SwissProt: Q8VDM6 Mouse

Unigene: 155218 Human

Unigene: 718642 Human

Unigene: 254223 Mouse

Unigene: 95170 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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