background:
Endoribonuclease responsible for the inhibition of the translation by cleaving mRNA. Inhibits cell-free protein synthesis. Cleaves phosphodiester bonds only in single-stranded RNA.
Subcellular Location:
Cytoplasm. Nucleus. Mostly cytoplasmic but, in less differentiated cells occasionally nuclear.
Tissue Specificity:
Hepatocytes and renal distal tubular epithelial cells. Only weak expression in other tissues.
Similarity:
Belongs to the RutC family.
Database links:
Entrez Gene: 504390 Cow
Entrez Gene: 100861379 Goat
Entrez Gene: 10247 Human
Omim: 602487 Human
SwissProt: Q3T114 Cow
SwissProt: P80601 Goat
SwissProt: P52758 Human
Unigene: 18426 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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