Rabbit Anti-HIV TAT specific factor 1/FITC Conjugated antibody

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Cofactor required for Tat activation of HIV 1 transcription; dJ196E23.2; HIV Tat specific factor 1; HTATSF1; HTSF-1; HTSF1; RP1 196E23.2 001; TAT SF1; Tat-SF1.

Cat:

SL17453R-FITC

Species Reactivity：

(predicted: Human,Mouse,)

Immunogen：

KLH conjugated synthetic peptide derived from human HIV TAT specific factor 1

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

86kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
The protein encoded by this gene functions as a cofactor for the stimulation of transcriptional elongation by HISLV1 Tat, which binds to the HISLV1 promoter through Tat-TAR interaction. This protein may also serve as a dual-function factor to couple transcription and splicing and to facilitate their reciprocal activation. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Sep 2009]

Function:
HIV TAT specific factor(a.k.a. HTATSF1, Tat-SF1 or HTSF1) is an 86 kDa general transcription factor that plays a role in the process of transcription elongation. However, in HISLVinfected cells, this factor is up-regulated by HIV Nef and gp120 and acts as a co-factor for the Tat-enhanced transcription of the HIV virus.

Subcellular Location:
Nuclear

Database links:

Entrez Gene: 27336 Human

Entrez Gene: 72459 Mouse

Entrez Gene: 317612 Rat

Omim: 300346 Human

SwissProt: O43719 Human

SwissProt: Q8BGC0 Mouse

Unigene: 204475 Human

Unigene: 2152 Mouse

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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