Rabbit Anti-HIVEP1/FITC Conjugated antibody

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Cirhin interaction protein; CIRIP; CRYBP1; GAAP; Gate keeper of apoptosis-activating protein; HIV EP1; HIV-EP1; HIVEP 1; Hivep1; Human immunodeficiency virus type I enhancer binding protein 1; Human immunodeficiency virus type I enhancer-binding

Cat:

SL17459R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Dog,Pig,Cow,Horse,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human HIVEP1

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

297kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
This protein specifically binds to the DNA sequence 5'-GGGACTTTCSLC3' which is found in the enhancer elements of numerous viral promoters such as those of SV40, CMV, or HISLV1. In addition, related sequences are found in the enhancer elements of a number of cellular promoters, including those of the class I MHC, interleukin-2 receptor, and interferon-beta genes. It may act in T-cell activation. Involved in activating HISLV1 gene expression. Isoform 2 and isoform 3 also bind to the IPCS (IRF1 and p53 common sequence) DNA sequence in the promoter region of interferon regulatory factor 1 and p53 genes and are involved in transcription regulation of these genes. Isoform 2 does not activate HISLV1 gene expression. Isoform 2 and isoform 3 may be involved in apoptosis.

Subcellular Location:
Cytoplasm. Nucleus and Nucleus.

Similarity:
Contains 5 C2H2-type zinc fingers.

Database links:

Entrez Gene: 3096 Human

Omim: 194540 Human

SwissProt: P15822 Human

Unigene: 567284 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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