Rabbit Anti-SIDT1/FITC Conjugated antibody

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AW045928; B830021E24Rik; FLJ20174; Msid2; OTTMUSP00000032144; SID 1; SID1; SID-1; SID1 transmembrane family member 1; SID1 transmembrane family, member 1; SIDT1; SIDT1_HUMAN.

Cat:

SL17484R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Pig,Cow,Rabbit,)

Immunogen：

KLH conjugated synthetic peptide derived from human SIDT1

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

92kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
SID-1 and SID-2 belong to the systemic RNA interference defective-1 (SID1) family of transmembrane proteins. SID-1, originally identified in C. elegans, is an 827 amino acid protein. It localizes to the cell membrane and contains eleven transmembrane domains. This suggests that SID-1 possibly functions as a channel protein. The overexpression of SID-1 enhances double stranded RNA (dsRNA) uptake in pancreatic ductal adenocarcinoma cells. SID-2, also first identified in C. elegans, is an 832 amino acid protein with multiple transmembrane domains. At least two isoforms exist for SID-2 due to alternative splicing. Isoform 2 contains an additional 21 amino acids after residue 387 and has an alternate sequence that is 8 amino acids shorter for residues 814 to 832 of isoform 1.

Subcellular Location:
Membrane.

Similarity:
Belongs to the SID1 family.

Database links:

Entrez Gene: 54847 Human

Entrez Gene: 64007 Mouse

Entrez Gene: 288109 Rat

Omim: 606816 Human

SwissProt: Q9NXL6 Human

SwissProt: Q6AXF6 Mouse

SwissProt: Q6Q3F5 Rat

Unigene: 591291 Human

Unigene: 242144 Mouse

Unigene: 51246 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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