Home > Product > Antibody > Rabbit Anti-SPATA9/FITC Conjugated antibody
FLJ35906; NYD SP16; spermatogenesis associated 9; Spermatogenesis associated protein 9; Testis development protein NYD SP16.
Cat:
SL17635R-FITC
Species Reactivity:
Mouse,Rat,(predicted: Human,Pig,Cow,Sheep,)
Immunogen:
KLH conjugated synthetic peptide derived from human SPATA9
Format:
Lyophilized or Liquid
Storage instructions:
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant
Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
Calculated MW:
29kDa
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Unit:
Price: $
Product PDFs
Datasheet:


background:
SPATA9 is a 254 amino acid single-pass membrane protein that is highly expressed in testis and pancreas with low expression in heart, lung, and brain. A component of the sperm acrosome, SPATA9 may participate in sperm capacitation and acrosome reaction, and is therefore necessary for fertilization. SPATA9 is also suggested to be involved in testicular development/spermatogenesis and may be an important factor in male infertility. No expression of SPATA9 was found in patients affected by Sertoli-cell-only syndrome, also known as Del Castillo syndrome or germ cell aplasia, which is characterized by male sterility without sexual abnormality. SPATA9 is encoded by a gene located on human chromosome 5, which consists of about 181 million base pairs, encodes around 1,000 genes and represents about 6% of human genomic DNA.

Function:
SPATA9 may play a role in testicular development/spermatogenesis and may be an important factor in male infertility. Three named isoforms exist.

Subcellular Location:
Membrane; Single-pass membrane protein

Database links:

Entrez Gene: 83890 Human

Omim: 608039 Human

SwissProt: Q9BWV2 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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