Rabbit Anti-SPOCK3/FITC Conjugated antibody

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HSAJ1454; OTTHUMP00000219853; OTTHUMP00000219854; OTTHUMP00000219857; OTTHUMP00000219858; OTTHUMP00000219862; OTTHUMP00000219864; OTTHUMP00000219865; OTTHUMP00000219866; OTTHUMP00000219867; OTTHUMP00000219868; Sparc/osteonectin, cwcv and kazal

Cat:

SL17683R-FITC

Species Reactivity：

Human,(predicted: Mouse,Rat,Dog,)

Immunogen：

KLH conjugated synthetic peptide derived from human SPOCK3

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

49kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
This gene encodes a member of a novel family of calcium-binding proteoglycan proteins that contain thyroglobulin type-1 and Kazal-like domains. The encoded protein and may play a role in adult T-cell leukemia by inhibiting the activity of membrane-type matrix metalloproteinases. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011]

Function:
SPOCK3 may participate in diverse steps of neurogenesis. It inhibits the processing of pro-matrix metalloproteinase 2 (MMP-2) by MT1-MMP and MT3-MMP and may also interfere with tumor invasion.

Subcellular Location:
Secreted, extracellular space, extracellular matrix.

Similarity:
Contains 1 Kazal-like domain. Contains 1 thyroglobulin type-1 domain.

Database links:

Entrez Gene: 50859 Human

Entrez Gene: 72902 Mouse

Entrez Gene: 301284 Rat

Omim: 607989 Human

SwissProt: Q9BQ16 Human

SwissProt: Q8BKV0 Mouse

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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