background:
MOBKL2A is a 217 amino acid protein that regulates kinase activity. A member of the MOB1/phocein family, MOBKL2A is encoded by a gene that maps to human chromosome 19. Consisting of around 63 million bases with over 1,400 genes, chromosome 19 makes up over 2% of human genomic DNA. Chromosome 19 includes a diversity of interesting genes and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin superfamily members including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family, and Fc?receptors. Key genes for eye color and hair color also map to chromosome 19. Peutz-Jeghers syndrome, spinocerebellar ataxia type 6, the stroke disorder CADASIL, hypercholesterolemia and insulin-dependent diabetes have been linked to chromosome 19.
Function:
May regulate the activity of kinases.
Similarity:
Belongs to the MOB1/phocein family.
Database links:
Entrez Gene: 126308 Human
Entrez Gene: 208228 Mouse
Entrez Gene: 362833 Rat
SwissProt: Q96BX8 Human
SwissProt: Q8BSU7 Mouse
Unigene: 86912 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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