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Rabbit Anti-MRPS11/FITC Conjugated antibody
background:
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that contains a high level of sequence similarity with ribosomal protein S11P family members. A pseudogene corresponding to this gene is found on chromosome 20. Sequence analysis identified two transcript variants that encode different protein isoforms. [provided by RefSeq, Jul 2008]
Subcellular Location:
Mitochondrion.
Similarity:
Belongs to the ribosomal protein S11P family.
Database links:
Entrez Gene: 64963 Human
Entrez Gene: 67994 Mouse
Entrez Gene: 499185 Rat
Omim: 611977 Human
SwissProt: P82912 Human
SwissProt: Q9DCA2 Mouse
Unigene: 111286 Human
Unigene: 297033 Mouse
Unigene: 759 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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