Rabbit Anti-TNRC5/PRAT4A/FITC Conjugated antibody

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CAG repeat containing; CAG4A; Canopy 3 homolog; cnpy3; CNPY3_HUMAN; CTG repeat protein 4a; ERDA 5; ERDA5; Expanded repeat domain CAG/CTG 5; Expanded repeat-domain protein CAG/CTG 5; OTTHUMP00000016408; PRAT4A; Protein associated with Tlr4; Pr

Cat:

SL18160R-FITC

Species Reactivity：

Mouse,(predicted: Human,Rat,Dog,Pig,Cow,Horse,Rabbit,)

Immunogen：

KLH conjugated synthetic peptide derived from human TNRC5/PRAT4A

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

31kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
PRAT4A is associated with the immature form of TLR4 (MIM 603030) and regulates its cell surface expression (Wakabayashi et al., 2006 [PubMed 16849487]).[supplied by OMIM, Mar 2008]

Function:
Toll-like receptor (TLR)-specific co-chaperone for HSP90B1. Required for proper TLR folding, except that of TLR3, and hence controls TLR exit from the endoplasmic reticulum. Consequently, required for both innate and adaptative immune responses.

Subcellular Location:
Endoplasmic reticulum.

Similarity:
Belongs to the canopy family.
Contains 1 saposin B-type domain.

Database links:

Entrez Gene: 10695 Human

Entrez Gene: 685174 Rat

Omim: 610774 Human

SwissProt: Q9BT09 Human

SwissProt: A5GFQ5 Pig

Unigene: 414099 Human

Unigene: 43984 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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