Rabbit Anti-Invadolysin/FITC Conjugated antibody

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Gp63; GP63 like; INV; LMLN_HUMAN; IX14; Leishmanolysin Like Peptidase; leishmanolysin-like (metallopeptidase M8 family); LMLN; Msp.

Cat:

SL1836R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Horse,Rabbit,)

Immunogen：

KLH conjugated synthetic peptide derived from human Invadolysin

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

74kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
This gene encodes a zinc-metallopeptidase. The encoded protein may play a role in cell migration and invasion. Studies of a similar protein in Drosophila indicate a potential role in mitotic progression. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2009]

Function:
Invadolysin, also known as Leismanolysin-Like proteinase, is a metalloproteinase of the MA clan, family M8, which is distinguished from the other families of metalloproteinases by an insert in the zinc binding site. The “classical” zinc binding motif of HExxHxxxxH contains an insert of 65 residues in the Leishmania form of Leishmanolysin, and varies from 62-105 residues amongst different parasite leishmanolysin isoforms.

Subcellular Location:
Cytoplasmic

Tissue Specificity:
Expressed in all cell lines analyzed.

Similarity:
Belongs to the peptidase M8 family.

Database links:

Entrez Gene: 89782 Human

Omim: 609380 Human

SwissProt: Q96KR4 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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