Rabbit Anti-LCLAT1/FITC Conjugated antibody

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1-acylglycerol-3-phosphate O-acyltransferase 8; 1-AGP acyltransferase 8; 1-AGPAT 8; 1AGPAT8; Acyl-CoA:lysocardiolipin acyltransferase 1; AGPAT8; ALCAT1; HSRG1849; lclat1; LCLT1_HUMAN; LYCAT; Lysocardiolipin acyltransferase 1; UNQ1849; UNQ1849

Cat:

SL18190R-FITC

Species Reactivity：

Mouse,(predicted: Human,Rat,Dog,Cow,Horse,Rabbit,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human LCLAT1

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

49kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
Acyl-CoA:lysocardiolipin acyltransferase. Possesses both lysophosphatidylinositol acyltransferase (LPIAT) and lysophosphatidylglycerol acyltransferase (LPGAT) activities. Recognizes both monolysocardiolipin and dilysocardiolipin as substrates with a preference for linoleoyl-CoA and oleoyl-CoA as acyl donors. Acts as a remodeling enzyme for cardiolipin, a major membrane polyglycerophospholipid. Converts lysophosphatidic acid (LPA) into phosphatidic acid (PA) with a relatively low activity. Required for establishment of the hematopoietic and endothelial lineages.

Subcellular Location:
Endoplasmic reticulum membrane.

Tissue Specificity:
Expressed at higher level in heart, kidney and pancreas than in brain, spleen, liver, lung, small intestine and placenta.

Similarity:
Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

Database links:

Entrez Gene: 253558 Human

Entrez Gene: 225010 Mouse

Entrez Gene: 100217396 Pig

Omim: 614241 Human

SwissProt: Q6UWP7 Human

SwissProt: Q3UN02 Mouse

Unigene: 413648 Human

Unigene: 662770 Human

Unigene: 329194 Mouse

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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