Rabbit Anti-LENG4/FITC Conjugated antibody

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1-acylglycerophosphatidylinositol O-acyltransferase; Bladder and breast carcinoma-overexpressed gene 1 protein; h-mboa-7; Leukocyte receptor cluster member 4; LPIAT; LPLAT 7; Lyso-PI acyltransferase; Lysophosphatidylinositol acyltransferase; Lysop

Cat:

SL18219R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Dog,Cow,)

Immunogen：

KLH conjugated synthetic peptide derived from human LENG4

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

53kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
This gene encodes a member of the membrane-bound O-acyltransferases family of integral membrane proteins that have acyltransferase activity. The encoded protein is a lysophosphatidylinositol acyltransferase that has specificity for arachidonoyl-CoA as an acyl donor. This protein is involved in the reacylation of phospholipids as part of the phospholipid remodeling pathway known as the Land cycle. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2009]

Function:
Acyltransferase which mediates the conversion of lysophosphatidylinositol (1-acylglycerophosphatidylinositol or LPI) into phosphatidylinositol (1,2-diacyl-sn-glycero-3-phosphoinositol or PI) (LPIAT activity). Prefers arachidonoyl-CoA as the acyl donor. Lysophospholipid acyltransferases (LPLATs) catalyze the reacylation step of the phospholipid remodeling pathway also known as the Lands cycle.

Subcellular Location:
Membrane.

Tissue Specificity:
Overexpressed in metastatic breast and bladder carcinomas relative to normal breast epithelium and urothelium.

Similarity:
Belongs to the membrane-bound acyltransferase family.

Database links:

Entrez Gene: 79143 Human

Entrez Gene: 77582 Mouse

SwissProt: Q96N66 Human

SwissProt: Q8CHK3 Mouse

Unigene: 467279 Human

Unigene: 482149 Mouse

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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