background:
This gene is a member of the lipoma HMGIC fusion partner (LHFP) gene family, which is a subset of the superfamily of tetraspan transmembrane protein encoding genes. Mutations in one LHFP-like gene result in deafness in humans and mice, and a second LHFP-like gene is fused to a high-mobility group gene in a translocation-associated lipoma. Alternatively spliced transcript variants have been found, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
Subcellular Location:
Membrane.
Tissue Specificity:
Widely expressed. Expressed at high levels in lung, thymus, skeletal muscle, colon and ovary.
Similarity:
Belongs to the LHFP family.
Database links:
Entrez Gene: 340596 Human
Omim: 300566 Human
SwissProt: Q86WI0 Human
Unigene: 297420 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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