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Rabbit Anti-LIPC/FITC Conjugated antibody
background:
LIPC encodes hepatic triglyceride lipase, which is expressed in liver. LIPC has the dual functions of triglyceride hydrolase and ligand/bridging factor for receptor-mediated lipoprotein uptake. [provided by RefSeq, Jul 2008]
Function:
Hepatic lipase has the capacity to catalyze hydrolysis of phospholipids, mono-, di-, and triglycerides, and acyl-CoA thioesters. It is an important enzyme in HDL metabolism. Hepatic lipase binds heparin.
Subcellular Location:
Secreted.
DISEASE:
Defects in LIPC are the cause of hepatic lipase deficiency (HL deficiency) [MIM:151670].
Similarity:
Belongs to the AB hydrolase superfamily. Lipase family.
Contains 1 PLAT domain.
Database links:
Entrez Gene: 3990 Human
Omim: 151670 Human
SwissProt: P11150 Human
Unigene: 654472 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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