Rabbit Anti-LPGAT1/FITC Conjugated antibody

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Acyl CoA:lysophosphatidylglycerol acyltransferase 1; Acyl-CoA:lysophosphatidylglycerol acyltransferase 1; FAM34A; FAM34A1; Family with sequence similarity 34 member A; KIAA0205; LGAT1_HUMAN; Lpgat1; lysophosphatidylglycerol acyltransferase 1; NET

Cat:

SL18347R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Chicken,Pig,)

Immunogen：

KLH conjugated synthetic peptide derived from human LPGAT1

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

43kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
Acyl-CoA:lysophosphatidylglycerol (LPG) acyltransferase catalyzes the reacylation of LPG to phosphatidylglycerol, a membrane phospholipid that is an important precursor for the synthesis of cardiolipin (Yang et al., 2004 [PubMed 15485873]).[supplied by OMIM, Mar 2008]

Function:
Lysophoshatidylglycerol (LPG) specific acyltransferase that recognizes various acyl-CoAs and LPGs as substrates but demonstrates a clear preference for long chain saturated fatty acyl-CoAs and oleoyl-CoA as acyl donors. Prefers oleoyl-LPG over palmitoyl-LPG as an acyl receptor and oleoyl-CoA over lauroyl-CoA as an acyl donor.

Subcellular Location:
Endoplasmic reticulum membrane.

Tissue Specificity:
Highly expressed in liver and placenta. Also expressed in peripheral blood, lung, kidney and brain. Detected at lower levels in colon.

Similarity:
Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

Database links:

Entrez Gene: 541208 Cow

Entrez Gene: 609933 Dog

Entrez Gene: 9926 Human

Entrez Gene: 226856 Mouse

Entrez Gene: 679692 Rat

Omim: 610473 Human

SwissProt: Q92604 Human

SwissProt: Q91YX5 Mouse

Unigene: 725196 Human

Unigene: 277958 Mouse

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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