Rabbit Anti-LRP11/FITC Conjugated antibody

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bA350J20.3; Low density lipoprotein receptor related protein 11; LRP 11; MANSC3.

Cat:

SL18361R-FITC

Species Reactivity：

Human,

Immunogen：

KLH conjugated synthetic peptide derived from human LRP11

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

49kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
LRP11 is a 500 amino acid single-pass type I membrane protein that exists as two alternatively spliced isoforms. LRP11 is encoded by a gene located on human chromosome 6q25.1. Chromosome 6 contains 170 million base pairs and comprises nearly 6% of the human genome. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus. Additionally, Porphyria cutanea tarda, Parkinson's disease, Stickler syndrome and a susceptibility to bipolar disorder are all associated with genes that map to chromosome 6.

Function:
LRP11 belongs to the LDLR family. It contains one LDL-receptor class A domain, one MANEC domain and one PKD domain. There are two named isoforms.

Subcellular Location:
Membrane; Single pass type I membrane protein

Similarity:
Belongs to the LDLR family.
Contains 1 LDL-receptor class A domain.
Contains 1 MANSC domain.
Contains 1 PKD domain.

Database links:

Entrez Gene: 84918 Human

SwissProt: Q86VZ4 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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