Home > Product > Antibody > Rabbit Anti-LSM5/FITC Conjugated antibody
2010208O10Rik; 2310034K10Rik; FLJ12710; LSM5; LSM5 homolog; LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae); LSM5_HUMAN; U6 small nuclear RNA associated (S. cerevisiae); U6 snRNA-associated Sm-like protein LSm5; YER146W.
Cat:
SL18430R-FITC
Species Reactivity:
(predicted: Human,Mouse,Rat,Pig,)
Immunogen:
KLH conjugated synthetic peptide derived from human LSM5
Format:
Lyophilized or Liquid
Storage instructions:
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant
Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
Calculated MW:
10kDa
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Unit:
Price: $
Product PDFs
Datasheet:


background:
Sm-like proteins were identified in a variety of organisms based on sequence homology with the Sm protein family (see SNRPD2; MIM 601061). Sm-like proteins contain the Sm sequence motif, which consists of 2 regions separated by a linker of variable length that folds as a loop. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing.[supplied by OMIM, Apr 2004]

Function:
Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA, thereby facilitating U4/U6 duplex formation in vitro.

Subcellular Location:
Nucleus.

Similarity:
Belongs to the snRNP Sm proteins family.

Database links:

Entrez Gene: 23658 Human

Entrez Gene: 100044729 Mouse

Entrez Gene: 66373 Mouse

Entrez Gene: 306222 Rat

Omim: 607285 Human

SwissProt: Q9Y4Y9 Human

SwissProt: P62322 Mouse

Unigene: 424908 Human

Unigene: 25642 Mouse

Unigene: 8983 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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