Rabbit Anti-LSM8/FITC Conjugated antibody

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2010003I05Rik; AW214405; LSM8 homolog, U6 small nuclear RNA associated (S. cerevisiae); MGC127377; YJR022W.

Cat:

SL18433R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Chicken,Pig,Cow,Horse,Rabbit,Sheep,Guinea Pig,)

Immunogen：

KLH conjugated synthetic peptide derived from human LSM8

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

10kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
This gene encodes a member of the like-Sm family of proteins. The encoded protein consists of a closed barrel shape, made up of five anti-parallel beta strands and an alpha helix. This protein partners with six paralogs to form a heteroheptameric ring which transiently binds U6 small nuclear RNAs and is involved in the general maturation of RNA in the nucleus.

Function:
Binds specifically to the 3'-terminal U-tract of U6 snRNA and is probably a component of the spliceosome.

Subunit:
LSm subunits form a heteromer with a doughnut shape.

Subcellular Location:
Nuclear

Similarity:
Belongs to the snRNP Sm proteins family.

Database links:

Entrez Gene: 417765 Chicken

Entrez Gene: 613630 Cow

Entrez Gene: 51691 Human

Entrez Gene: 76522 Mouse

Entrez Gene: 296913 Rat

Omim: 607288 Human

SwissProt: Q3ZCE0 Cow

SwissProt: O95777 Human

SwissProt: Q6ZWM4 Mouse

SwissProt: B2RZB6 Rat

Unigene: 6283 Chicken

Unigene: 7372 Cow

Unigene: 657737 Human

Unigene: 14059 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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