Home > Product > Antibody > Rabbit Anti-LSM14A/C19orf13/FITC Conjugated antibody
AlphaSNBP; C19orf13; Chromosome 19 open reading frame 13; DKFZp434D1335; FAM61A; Family with sequence similarity 61 member A; hRAP55; hRAP55A; LS14A_HUMAN; LSM14 homolog A (SCD6 S cerevisiae); LSM14 homolog A; LSM14A; Protein FAM61A; Protein
Cat:
SL18437R-FITC
Species Reactivity:
(predicted: Human,Mouse,Rat,Chicken,Dog,Pig,Cow,Rabbit,Sheep,Guinea Pig,Cat,Danio)
Immunogen:
KLH conjugated synthetic peptide derived from human LSM14A/C19orf13
Format:
Lyophilized or Liquid
Storage instructions:
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant
Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
Calculated MW:
50kDa
More
Unit:
Price: $
Product PDFs
Datasheet:


background:
Sm-like proteins were identified in a variety of organisms based on sequence homology with the Sm protein family (see SNRPD2; 601061). Sm-like proteins contain the Sm sequence motif, which consists of 2 regions separated by a linker of variable length that folds as a loop. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing.[supplied by OMIM, Mar 2008]

Function:
Essential for formation of P-bodies, cytoplasmic structures that provide storage sites for non-translating mRNAs.

Subunit:
Component of a ribonucleoprotein (RNP) complex.

Subcellular Location:
Cytoplasm. Cytoplasm > P-body. Targeted to stress granules (SGs) in response to cellular stress.

Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR.

Similarity:
Belongs to the LSM14 family.
Contains 1 DFDF domain.

Database links:

Entrez Gene: 26065 Human

Entrez Gene: 67070 Mouse

Entrez Gene: 361554 Rat

Omim: 610677 Human

SwissProt: Q8ND56 Human

SwissProt: Q8K2F8 Mouse

Unigene: 407368 Human

Unigene: 276503 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Product Feedback Wall
Message :
Your Email :
Copyright © 2007-2018 Sunlong Medical All Rights Reserved.