Rabbit Anti-ZNF639/FITC Conjugated antibody

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ZNF 639; 6230400O18Rik; ANC 2H01; ANC_2H01; MGC157200; OTTHUMP00000212173; OTTHUMP00000212174; OTTHUMP00000212175; OTTHUMP00000212195; OTTHUMP00000212197; ZASC1; Zfp639; Zinc finger amplified in esophageal squamous cell carcinomas 1; Zinc fing

Cat:

SL18488R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,)

Immunogen：

KLH conjugated synthetic peptide derived from human ZNF639

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

56kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
ZNF639 is a 485 amino acid protein that localizes to the nucleus and contains five C2H2-type zinc fingers. One of several members of the Krueppel C2H2-type zinc-finger family, ZASC1 is thought to be involved in transcriptional regulation. The gene encoding ZASC1 maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3.

Function:
Binds DNA and may function as a transcriptional repressor.

Subunit:
Interacts with CTNNA2.

Subcellular Location:
Nucleus.

Similarity:
Belongs to the krueppel C2H2-type zinc-finger protein family.
Contains 8 C2H2-type zinc fingers.

Database links:

Entrez Gene: 51193 Human

Entrez Gene: 523536 Cow

Entrez Gene: 67778 Mouse

Entrez Gene: 683504 Rat

SwissProt: A5PK30 Cow

SwissProt: Q9UID6 Human

SwissProt: Q99KZ6 Mouse

SwissProt: Q5PPG4 Rat

Unigene: 632578 Human

Unigene: 285620 Mouse

Unigene: 116062 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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