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Rabbit Anti-ZC3HAV1L/C7orf39/FITC Conjugated antibody
background:
ZC3HAV1L is a 296 amino acid protein that contains two C3H1-type zinc fingers. Existing as two alternatively spliced isoforms, the gene encoding ZC3HAV1L maps to human chromosome 7, which houses over 1,000 genes and comprises nearly 5% of the human genome. Chromosome 7 has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. The deletion of a portion of the q arm of chromosome 7 is associated with Williams-Beuren syndrome, a condition characterized by mild mental retardation, an unusual comfort and friendliness with strangers and an elfin appearance. Deletions of portions of the q arm of chromosome 7 are also seen in a number of myeloid disorders including cases of acute myelogenous leukemia and myelodysplasia.
Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR.
Database links:
Entrez Gene: 92092 Human
SwissProt: Q96H79 Human
Unigene: 512833 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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