background:
MAK3 belongs to the acetyltransferase family, MAK3 subfamily. It contains one N-acetyltransferase domain. It is a probable N-acetyltransferase.
Function:
Catalytic subunit of the N-terminal acetyltransferase C (NatC) complex. Catalyzes acetylation of the N-terminal methionine residues of peptides beginning with Met-Leu-Ala and Met-Leu-Gly. Necessary for the lysosomal localization and function of ARL8B sugeesting that ARL8B is a NatC substrate.
Subunit:
Component of the N-terminal acetyltransferase C (NatC) complex, which is composed of NAA35, NAA38 and NAA30.
Subcellular Location:
Cytoplasmic
Similarity:
Belongs to the acetyltransferase family. MAK3 subfamily.
Contains 1 N-acetyltransferase domain.
Database links:
Entrez Gene: 122830 Human
Entrez Gene: 70646 Mouse
Entrez Gene: 288108 Rat
SwissProt: Q147X3 Human
SwissProt: Q8CES0 Mouse
Unigene: 165465 Human
Unigene: 275688 Mouse
Unigene: 15205 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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