Rabbit Anti-MAK10/FITC Conjugated antibody

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bA379P1.1; Embryonic growth-associated protein homolog; FLJ21613; FLJ22643; N(alpha)-acetyltransferase 35, NatC auxiliary subunit; N-alpha-acetyltransferase 35; N-alpha-acetyltransferase 35, NatC auxiliary subunit; NAA35; NAA35_HUMAN; NatC auxili

Cat:

SL18636R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Chicken,Pig,Cow,Horse,Rabbit,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human MAK10

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

84kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
MAK10 is a 725 amino acid cytoplasmic protein that regulates proliferation of smooth muscle cells. A member of the MAK10 family, MAK10 exists as a component of the N-terminal acetyltransferase C (NatC) complex along with LSmD1 and NAT-12. The gene encoding MAK10 maps to human chromosome 9, which houses over 900 genes and comprises nearly 4% of the human genome. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, and Familial dysautonomia, are both associated with chromosome 9. Notably, chromosome 9 encompasses the largest interferon family gene cluster.

Function:
Regulates proliferation of smooth muscle cells (By similarity). Component of the N-terminal acetyltransferase C (NatC) complex which may catalyze acetylation of N-terminal methionine residues.

Subcellular Location:
Cytoplasm.

Similarity:
Belongs to the MAK10 family.

Database links:

Entrez Gene: 60560 Human

Entrez Gene: 78689 Mouse

Entrez Gene: 64472 Rat

SwissProt: Q5VZE5 Human

SwissProt: Q6PHQ8 Mouse

SwissProt: Q6DKG0 Rat

Unigene: 47298 Human

Unigene: 253902 Mouse

Unigene: 73698 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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