Rabbit Anti-MAP1D/FITC Conjugated antibody

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AMP1D_HUMAN; CDS of metAP 3 within PCR fragment; M ethionine aminopeptidase 1D, mitochondrial precursor; MAP 1D; MAP1D; MetAP 1D; Metap1l; Methionine aminopeptidase 1D; Methionine aminopeptidase 1D, mitochondrial; Methionyl aminopeptidase type 1D

Cat:

SL18659R-FITC

Species Reactivity：

Human,(predicted: Mouse,Dog,Cow,Horse,Rabbit,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human MAP1D

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

35kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
The N-terminal methionine excision pathway is an essential process in which the N-terminal methionine is removed from many proteins, thus facilitating subsequent protein modification. In mitochondria, enzymes that catalyze this reaction are celled methionine aminopeptidases (MetAps, or MAPs; EC 3.4.11.18) (Serero et al., 2003 [PubMed 14532271]).[supplied by OMIM, Mar 2008]

Function:
Removes the amino-terminal methionine from nascent proteins (By similarity). May play a role in colon tumorigenesis.

Subcellular Location:
Mitochondrion.

Tissue Specificity:
Overexpressed in colon cancer cell lines and colon tumors as compared to normal tissues (at protein level).

Similarity:
Belongs to the peptidase M24A family.

Database links:

Entrez Gene: 254042 Human

Entrez Gene: 66559 Mouse

Entrez Gene: 311748 Rat

Omim: 610267 Human

SwissProt: Q6UB28 Human

SwissProt: Q9CPW9 Mouse

Unigene: 298250 Human

Unigene: 152796 Mouse

Unigene: 4826 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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