Rabbit Anti-MCTP2/FITC Conjugated antibody

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FLJ11175; FLJ33303; MGC111402; Multiple C2 and transmembrane domain containing protein 2; Multiple C2 domains, transmembrane 2; Multiple C2-domains with two transmembrane regions 2.

Cat:

SL18738R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Dog,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human MCTP2

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

100kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
MCTP2 is an 878 amino acid multi-pass membrane protein that belongs to the MCTP family. Existing as five alternatively spliced isoforms, MCTP1 binds calcium via its C2 domains in the absence of phospholipids, and is encoded by a gene that maps to human chromosome 15q26.2. Chromosome 15 houses over 700 genes and comprises nearly 3% of the human genome. Angelman syndrome, Prader-Willi syndrome, Tay-Sachs disease and Marfan syndrome are all associated with defects in chromosome 15-localized genes.

Function:
MCTP2 contains C2 domains which bind calcium in the absence of phospholipids. There are 5 isoforms produced by alternative splicing.

Subcellular Location:
Cell Membrane; multipass membrane protein

Similarity:
Belongs to the MCTP family.
Contains 3 C2 domains.

Database links:

Entrez Gene: 55784 Human

Entrez Gene: 28849 Mouse

Entrez Gene: 308742 Rat

SwissProt: Q6DN12 Human

SwissProt: Q5RJH2 Mouse

Unigene: 592017 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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