Rabbit Anti-MCTP1/FITC Conjugated antibody

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2810465F10Rik; FLJ22344; MCTP 1; Multiple C2 and transmembrane domain containing protein 1; Multiple C2 domains transmembrane 1; Multiple C2 domains with two transmembrane regions 1; OTTMUSP00000031345; RGD1305199.

Cat:

SL18737R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,)

Immunogen：

KLH conjugated synthetic peptide derived from human MCTP1

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

115kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
MCTP1 is a 999 amino acid multi-pass membrane protein that belongs to the MCTP family. Existing as five alternatively spliced isoforms, MCTP1 binds calcium via its C2 domains in the absence of phospholipids. The gene encoding MCTP1 maps to human chromosome 5, which contains 181 million base pairs and comprises nearly 6% of the human genome. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.

Function:
MCTP1 binds calcium via the C2 domains in the absence of phospholipids. There are 5 named isoforms.

Subcellular Location:
Membrane; Multi-pass membrane protein.

Database links:

Entrez Gene: 79772 Human

Entrez Gene: 78771 Mouse

Entrez Gene: 309928 Rat

SwissProt: Q6DN14 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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