Home > Product > Antibody > Rabbit Anti-MED6/FITC Conjugated antibody
Activator recruited cofactor 33 kDa; Activator-recruited cofactor 33 kDa component; ARC33; hMed6; MED6; MED6_HUMAN; Mediator complex subunit 6; Mediator of RNA polymerase II transcription subunit 6; NY REN 28 antigen; Renal carcinoma antigen NY-R
Cat:
SL18772R-FITC
Species Reactivity:
(predicted: Human,Mouse,Rat,Pig,Cow,Horse,Rabbit,)
Immunogen:
KLH conjugated synthetic peptide derived from human MED6
Format:
Lyophilized or Liquid
Storage instructions:
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant
Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
Calculated MW:
28kDa
More
Unit:
Price: $
Product PDFs
Datasheet:


Function:
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.

Subcellular Location:
Nucleus.

Similarity:
Belongs to the Mediator complex subunit 6 family.

Database links:

Entrez Gene: 10001 Human

Entrez Gene: 426282 Chicken

Entrez Gene: 505293 Cow

Entrez Gene: 69792 Mouse

Entrez Gene: 29936 Rat

Omim: 602984 Human

SwissProt: Q3SZY9 Cow

SwissProt: O75586 Human

SwissProt: Q921D4 Mouse

Unigene: 497353 Human

Unigene: 279993 Mouse

Unigene: 97814 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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