Function:
Elicits growth inhibition on melanoma cells in vitro as well as some other neuroectodermal tumors, including gliomas.
Subcellular Location:
Secreted.
Tissue Specificity:
All malignant melanoma cell lines tested and infrequently in glioma cell lines.
Post-translational modifications:
May possess two intramolecular disulfide bonds.
Similarity:
Belongs to the MIA/OTOR family.
Contains 1 SH3 domain.
Database links:
Entrez Gene: 100064799 Horse
Entrez Gene: 8190 Human
Entrez Gene: 81510 Rat
Omim: 601340 Human
SwissProt: Q16674 Human
SwissProt: Q62946 Rat
Unigene: 646364 Human
Unigene: 10660 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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