Rabbit Anti-MEMO1/FITC Conjugated antibody

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C21orf19-like protein; C2orf4; CGI 27; DKFZp434I0135; FLJ25031; HCV NS5A-transactivated protein 7; Hepatitis C virus NS5A-transactivated protein 7; Mediator of cell motility 1; Mediator of ErbB2-driven cell motility 1; MEMO; Memo-1; memo1; MEM

Cat:

SL18787R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Dog,Cow,Horse,)

Immunogen：

KLH conjugated synthetic peptide derived from human MEMO1

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

34kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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Function:
May control cell migration by relaying extracellular chemotactic signals to the microtubule cytoskeleton. Mediator of ERBB2 signaling. The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. It controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity. In turn, membrane-bound APC allows the localization of the MACF1 to the cell membrane, which is required for microtubule capture and stabilization. Is required for breast carcinoma cell migration.

Subunit:
Interacts with ERBB2 phosphorylated on 'Tyr-1248'.

Similarity:
Belongs to the UPF0103 family.

Database links:

Entrez Gene: 51072 Human

Entrez Gene: 63163 Cow

Entrez Gene: 76890 Mouse

Entrez Gene: 298787 Rat

Entrez Gene: 32772 Zebrafish

Omim: 611786 Human

SwissProt: Q2HJH7 Cow

SwissProt: Q9Y316 Human

SwissProt: Q91VH6 Mouse

SwissProt: Q4QQR9 Rat

SwissProt: Q803S3 Zebrafish

Unigene: 43892 Cow

Unigene: 444969 Human

Unigene: 311874 Mouse

Unigene: 22312 Rat

Unigene: 14259 Zebrafish

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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