Rabbit Anti-RQCD1/FITC Conjugated antibody

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CAF40; CCR4-NOT transcription complex subunit 9; Cell differentiation protein RCD1 homolog; CNOT9; CT129; Homo sapiens protein involved in sexual development complete cds; Rcd 1; Rcd-1; Rcd1 (required for cell differentiation, S.pombe) homolog 1;

Cat:

SL18842R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,Zebrafish,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human RQCD1

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

33kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
This gene encodes a member of the highly conserved RCD1 protein family. The encoded protein is a transcriptional cofactor and a core protein of the CCR4-NOT complex. It may be involved in signal transduction as well as retinoic acid-regulated cell differentiation and development. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Oct 2012]

Function:
Transcription factor that down-regulates MYB- and JUN-dependent transcription. May play a role in cell differentiation (By similarity). Can bind oligonucleotides, such as poly-G, poly-C or poly-T (in vitro), but the physiological relevance of this is not certain. Does not bind poly-A.

Subcellular Location:
Nucleus. Cytoplasm > P-body. NANOS2 promotes its localization to P-body.

Tissue Specificity:
Detected in spleen, thymus, prostate, testis, ovary and intestine.

Similarity:
Belongs to the RCD1 family.

Database links:

Entrez Gene: 9125 Human

Omim: 612054 Human

SwissProt: Q92600 Human

Unigene: 148767 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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