Rabbit Anti-RRP12/FITC Conjugated antibody

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ribosomal RNA processing 12 homolog (S. cerevisiae); Rrp12; RRP12-like protein; RRP12_HUMAN.

Cat:

SL18857R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Chicken,Dog,Cow,Horse,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human RRP12

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

144kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
RRP12 is a 1,297 amino acid single-pass membrane protein that participates in ribosomal assembly. Expressed in testis and ovary, RRP12 belongs to the RRP12 family and localizes to the nucleus. RRP12 may be involved in coupling the control of ribosome production to the regulation of other cellular processes during cell cycle progression. In conjunction with Dim2, RRP12 is thought to be involved in the nucleocytoplasmic translocation of pre-ribosomes during ribosome assembly. RRP12 exists two alternatively spliced isoforms and is encoded by a gene located on human chromosome 10q24.1.

Subcellular Location:
Nucleus > nucleolus. Nucleus membrane.

Tissue Specificity:
Weakly expressed. Expressed at intermediate level in testis and ovary.

Similarity:
Belongs to the RRP12 family.

Database links:

Entrez Gene: 23223 Human

Entrez Gene: 107094 Mouse

SwissProt: Q5JTH9 Human

SwissProt: Q6P5B0 Mouse

Unigene: 434251 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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