Home > Product > Antibody > Rabbit Anti-MGAT4A/FITC Conjugated antibody
Alpha 1 3 mannosyl glycoprotein 4 beta N acetylglucosaminyltransferase A; Alpha 1 3 mannosyl glycoprotein beta 1 4 N acetylglucosaminyltransferase; GlcNAc T IVa; GNT IV; GNT IVA; MGT4A_HUMAN; GNTIV; GNTIVA; Mannosyl (alpha 1 3 ) glycoprotein beta 1
Cat:
SL18907R-FITC
Species Reactivity:
(predicted: Human,Mouse,Rat,Dog,Pig,Horse,Sheep,)
Immunogen:
KLH conjugated synthetic peptide derived from human MGAT4A
Format:
Lyophilized or Liquid
Storage instructions:
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant
Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
Calculated MW:
62kDa
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Unit:
Price: $
Product PDFs
Datasheet:


background:
MFSD8 is a 518 amino acid multi-pass membrane protein of the lysosome that is thought to function as a carrier protein that transports small solutes by way of chemiosmotic ion gradients. Expressed at low levels in many tissues, MFSD8 is encoded by a gene that maps to human chromosome 4q28.1. Defects in the gene encoding MFSD8 are the cause of a late infantile neuronal ceroid lipofuscinosis known as neuronal ceroid lipofuscinosis type 7 (CLN7). CLN7 is characterized by seizures, progressive dementia and visual failure.

Function:
May be a carrier that transport small solutes by using chemiosmotic ion gradients

Subcellular Location:
Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A soluble form: Secreted (By similarity).

Tissue Specificity:
Expressed at very low levels in all tissues tested.

Similarity:
Belongs to the glycosyltransferase 54 family.

Database links:

Entrez Gene: 6568 Human

Entrez Gene: 20504 Mouse

Entrez Gene: 171080 Rat

Omim: 182308 Human

SwissProt: Q14916 Human

SwissProt: Q61983 Mouse

SwissProt: Q62795 Rat

Unigene: 205816 Human

Unigene: 2656 Mouse

Unigene: 11150 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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