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Rabbit Anti-MGAT4A/FITC Conjugated antibody
background:
MFSD8 is a 518 amino acid multi-pass membrane protein of the lysosome that is thought to function as a carrier protein that transports small solutes by way of chemiosmotic ion gradients. Expressed at low levels in many tissues, MFSD8 is encoded by a gene that maps to human chromosome 4q28.1. Defects in the gene encoding MFSD8 are the cause of a late infantile neuronal ceroid lipofuscinosis known as neuronal ceroid lipofuscinosis type 7 (CLN7). CLN7 is characterized by seizures, progressive dementia and visual failure.
Function:
May be a carrier that transport small solutes by using chemiosmotic ion gradients
Subcellular Location:
Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A soluble form: Secreted (By similarity).
Tissue Specificity:
Expressed at very low levels in all tissues tested.
Similarity:
Belongs to the glycosyltransferase 54 family.
Database links:
Entrez Gene: 6568 Human
Entrez Gene: 20504 Mouse
Entrez Gene: 171080 Rat
Omim: 182308 Human
SwissProt: Q14916 Human
SwissProt: Q61983 Mouse
SwissProt: Q62795 Rat
Unigene: 205816 Human
Unigene: 2656 Mouse
Unigene: 11150 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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