Rabbit Anti-MONDOA/FITC Conjugated antibody

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MLX-interacting protein; BHLHE36; Class E basic helix loop helix protein 36; MIR; MLXIP; MONDOA; Transcriptional activator MondoA.

Cat:

SL18957R-FITC

Species Reactivity：

Mouse,Rat,(predicted: Human,Cow,Rabbit,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human MONDOA

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

101kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
This gene encodes a protein that functions as part of a heterodimer to activate transcription. The encoded protein forms a heterodimer with Max-like protein X (MLX) and is involved in the regulation of genes in response to cellular glucose levels. [provided by RefSeq, Mar 2014]

Function:
Binds DNA as a heterodimer with MLX and activates transcription. Binds to the canonical E box sequence 5'-CACGTG-3'. Plays a role in transcriptional activation of glycolytic target genes. Involved in glucose-responsive gene regulation.

Subunit:
Efficient DNA binding requires dimerization with another bHLH protein. Binds DNA as a homodimer or a heterodimer with MLX.

Subcellular Location:
Cytoplasm. Nucleus. Mitochondrion outer membrane.

Tissue Specificity:
Widely expressed in adult tissues. Most abundant in skeletal muscle. Ref.1

Similarity:
Contains 1 bHLH (basic helix-loop-helix) domain.

Database links:

Entrez Gene: 22877 Human

Entrez Gene: 208104 Mouse

Omim: 608090 Human

SwissProt: Q9HAP2 Human

SwissProt: Q2VPU4 Mouse

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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