Home > Product > Antibody > Rabbit Anti-NBAS/FITC Conjugated antibody
NBAS; NBAS_HUMAN; Neuroblastoma-amplified gene protein; Neuroblastoma-amplified sequence.
Cat:
SL19030R-FITC
Species Reactivity:
Rat,(predicted: Human,Mouse,Dog,Cow,Horse,)
Immunogen:
KLH conjugated synthetic peptide derived from human NBAS
Format:
Lyophilized or Liquid
Storage instructions:
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant
Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
Calculated MW:
269kDa
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Unit:
Price: $
Product PDFs
Datasheet:


background:
This gene encodes a protein with two leucine zipper domains, a ribosomal protein S14 signature domain and a Sec39 like domain. The protein is thought to be involved in Golgi-to-ER transport. Mutations in this gene are associated with short stature, optic nerve atrophy, and Pelger-Huet anomaly. [provided by RefSeq, Oct 2012]

Subcellular Location:
Cytoplasm

Tissue Specificity:
Broadly expressed, with highest levels in heart and skeletal muscle, and lowest levels in liver, small intestine and thymus. Up-regulated together with N-myc in some neuroblastoma cell lines.

DISEASE:
Short stature, optic nerve atrophy, and Pelger-Huet anomaly (SOPH) [MIM:62960]: An autosomal recessive syndrome characterized by severe postnatal growth retardation, facial dysmorphism with senile face, small hands and feet, normal intelligence, abnormal nuclear shape in neutrophil granulocytes (Pelger-Huet anomaly), and optic atrophy with loss of visual acuity and color vision.

Similarity:
Contains 2 WD repeats.

Database links:

Entrez Gene: 51594 Human

Omim: 608025 Human

SwissProt: A2RRP1 Human

Unigene: 467759 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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