Home > Product > Antibody > Rabbit Anti-NDUFB9/FITC Conjugated antibody
B22; CI B22; CI-B22; complex I B22 subunit; Complex I-B22; DKFZp566O173; FLJ22885; I B22; LYR motif containing protein 3; LYR motif-containing protein 3; LYRM3; NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa; NADH dehydrogenase [u
Cat:
SL19088R-FITC
Species Reactivity:
(predicted: Human,Mouse,Rat,Cow,Horse,)
Immunogen:
KLH conjugated synthetic peptide derived from human NDUFB9
Format:
Lyophilized or Liquid
Storage instructions:
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant
Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
Calculated MW:
22kDa
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Unit:
Price: $
Product PDFs
Datasheet:


background:
NDUFB9 is a 179 amino acid protein that belongs to the complex I LYR family. Localized to the inner mitochondrial membrane, as well as to the matrix side of the peripheral membrane, NDUFB9 functions as an accessory subunit of the multi-subunit mitochondrial membrane respiratory chain NADH dehydrogenase complex I. Complex I plays an important role in the transfer of electrons from NADH to the respiratory chain, a process that is essential for cellular respiration. The gene encoding NDUFB9 maps to human chromosome 8, which consists of nearly 146 million base pairs, houses more than 800 genes and is associated with a variety of diseases and malignancies. Schizophrenia, bipolar disorder, Trisomy 8, Pfeiffer syndrome, congenital hypothyroidism, Waardenburg syndrome and some leukemias and lymphomas are thought to occur as a result of defects in specific genes that map to chromosome 8.

Function:
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.

Subcellular Location:
Mitochondrion inner membrane.

Similarity:
Belongs to the complex I LYR family.

Database links:

Entrez Gene: 4715 Human

Entrez Gene: 66218 Mouse

Entrez Gene: 299954 Rat

Omim: 601445 Human

SwissProt: Q9Y6M9 Human

SwissProt: Q9CQJ8 Mouse

Unigene: 15977 Human

Unigene: 322294 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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