Home
>
Product
>
Antibody
>
Rabbit Anti-MXRA8/FITC Conjugated antibody
background:
MXRA8 is a 442 amino acid single-pass type I membrane protein that is implicated in the maintenance and maturation of the blood-brain barrier. Containing two Ig-like SLVtype (immunoglobulin-like) domains, MXRA8 exists as two alternatively spliced isoforms that are encoded by a gene that maps to human chromosome 1p36.33. Human chromosome 1 spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma
Function:
May play a role in the maturation and maintenance of blood-brain barrier.
Subcellular Location:
Membrane.
Similarity:
Contains 2 Ig-like SLVtype (immunoglobulin-like) domains.
Database links:
Entrez Gene: 54587 Human
Entrez Gene: 313770 Rat
SwissProt: Q9BRK3 Human
SwissProt: Q5XI43 Rat
Unigene: 515687 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
|
|