background:
The FYVE domain mediates the recruitment of proteins involved in membrane trafficking and cell signaling to phosphatidylinositol 3-phosphate-containing membranes. This protein contains two zinc-binding FYVE domains in tandem and is reported to localize to the Golgi apparatus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
Subcellular Location:
Golgi apparatus, Golgi stack. Note: Resides predominantly in the cisternal stacks of the Golgi.
Database links:
Entrez Gene: 53349 Human
Entrez Gene: 217695 Mouse
Entrez Gene: 299188 Rat
Omim: 605471 Human
SwissProt: Q9HSF4 Human
SwissProt: Q810J8 Mouse
Unigene: 335106 Human
Unigene: 59257 Mouse
Unigene: 205587 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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