Rabbit Anti-MYO1E/FITC Conjugated antibody

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FSGS6; HuncM-IC; MYO1C; Myo1e; MYO1E variant protein; MYO1E_HUMAN; Myosin heavy chain myr 3; Myosin IC, formerly; Myosin IE; Myosin-Ic; Myosin-Ie; Myr 3; Myr3; MYR5; Unconventional myosin 1E; Unconventional myosin Ie.

Cat:

SL19169R-FITC

Immunogen：

KLH conjugated synthetic peptide derived from human MYO1E

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

127kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
This gene encodes a member of the nonmuscle class I myosins which are a subgroup of the unconventional myosin protein family. The unconventional myosin proteins function as actin-based molecular motors. Class I myosins are characterized by a head (motor) domain, a regulatory domain and a either a short or long tail domain. Among the class I myosins, this protein is distinguished by a long tail domain that is involved in crosslinking actin filaments. This protein localizes to the cytoplasm and may be involved in intracellular movement and membrane trafficking. Mutations in this gene are the cause of focal segmental glomerulosclerosis-6. This gene has been referred to as myosin IC in the literature but is distinct from the myosin IC gene located on chromosome 17. [provided by RefSeq, Jan 2012]

Function:
Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments.

Similarity:
Contains 1 IQ domain.
Contains 1 myosin head-like domain.
Contains 1 SH3 domain.

Database links:

Entrez Gene: 4643 Human

Entrez Gene: 71602 Mouse

Entrez Gene: 25484 Rat

Omim: 601479 Human

SwissProt: Q12965 Human

SwissProt: Q63356 Mouse

SwissProt: Q63356 Rat

Unigene: 654506 Human

Unigene: 249311 Mouse

Unigene: 8737 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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