background:
Myosin XVI is a 1,858 amino acid protein that localizes to the cytoplasm and contains one IQ domain, two myosin head-like domains and seven ANK repeats. Existing as an unconventional Myosin, Myosin XVI is involved in intracellular movements related to Actin filaments and is thought to interact specifically with PP1 alpha and PP1 gamma, possibly playing a role in PP1-associated brain development. Multiple isoforms of Myosin XVI exist due to alternative splicing events.
Subcellular Location:
Cytoplasm. Found in puncta in soma and processes of astrocytes and dissociated cerebellar cells with the morphology of migrating granule cells.
Similarity:
Contains 7 ANK repeats.
Contains 1 IQ domain.
Contains 2 myosin head-like domains.
Database links:
Entrez Gene: 23026 Human
Entrez Gene: 244281 Mouse
Entrez Gene: 192253 Rat
SwissProt: Q9Y6X6 Human
SwissProt: Q5DU14 Mouse
SwissProt: Q9ERC1 Rat
Unigene: 656587 Human
Unigene: 422761 Mouse
Unigene: 207204 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
|
|