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Rabbit Anti-ZFYVE21/FITC Conjugated antibody
Function:
Plays a role in cell adhesion, and thereby in cell motility, regulating microtubule-induced PTK2/FAK1 dephosphorylation, an event important for focal adhesion disassemblya, as well as integrin beta-1/ITGB1 cell surface expression.
Subcellular Location:
Cell junction > focal adhesion. Cytoplasmic vesicle. Within cytoplasmic vesicles, partially colocalizes with EEA1, an endosomal marker.
Similarity:
Contains 1 FYVE-type zinc finger.
Database links:
Entrez Gene: 79038 Human
Entrez Gene: 68520 Mouse
Entrez Gene: 362789 Rat
Omim: 613504 Human
SwissProt: Q9BQ24 Human
SwissProt: Q8VCM3 Mouse
SwissProt: D3ZVP7 Rat
Unigene: 592322 Human
Unigene: 390497 Mouse
Unigene: 2468 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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