background:
Aquaporin 5 (AQP5) is a water channel protein. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). Aquaporin 5 plays a role in the generation of saliva, tears and pulmonary secretions. AQP0, AQP2, AQP5, and AQP6 are closely related and all map to 12q13. [provided by RefSeq, Jul 2008]
Function:
Forms a water-specific channel. Implicated in the generation of saliva, tears, and pulmonary secretions.
Subcellular Location:
Membrane; Multi-pass membrane protein.
Similarity:
Belongs to the MIP/aquaporin (TC 1.A.8) family.
Database links:
Entrez Gene: 362 Human
Entrez Gene: 11830 Mouse
Entrez Gene: 25241 Rat
Omim: 600442 Human
SwissProt: P55064 Human
SwissProt: Q9WTY4 Mouse
SwissProt: P47864 Rat
Unigene: 59623 Human
Unigene: 45580 Mouse
Unigene: 10066 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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