Rabbit Anti-NBEAL1/FITC Conjugated antibody

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neurobeachin-like 1; A530083I02Rik; ALS2CR16; ALS2CR17; Amyotrophic lateral sclerosis 2 (juvenile) chromosome region candidate 16; Amyotrophic lateral sclerosis 2 (juvenile) chromosome region candidate 17; Amyotrophic lateral sclerosis 2 chromosomal

Cat:

SL19216R-FITC

Species Reactivity：

(predicted: Human,)

Immunogen：

KLH conjugated synthetic peptide derived from human NBEAL1

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20癈. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antib

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

307 , 151kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
NBEAL1 is a 2,694 amino acid protein that belongs to the WD repeat Neurobeachin family. While highly expressed in kidney, brain, prostate and testis, NBEAL1 is also found at low levels in peripheral blood leukocytes, small intestine, ovary and colon. NBEAL1 contains one BEACH domain and two WD repeats, and undergoes alternative splicing to produce two isoforms. The gene encoding NBEAL1 maps to human chromosome 2, which consists of 237 million bases, encodes over 1,400 genes and makes up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2 including Harlequin icthyosis, sitosterolemia and Alstr鰉 syndrome.

Function:
Neurobeachin-like 1 belongs to the WD repeat neurobeachin family. It contains 1 BEACH domain and 2 WD repeats. Neurobeachin-like 1 is highly expressed in brain, kidney, prostate and testis and weakly expressed in ovary, small intestine, colon and peripheral blood leukocytes. It may be correlative to several tumors, such as ovary serous adenocarcinoma and metastasis mammary gland carcinoma breast.

Tissue Specificity:
Highly expressed in brain, kidney, prostate and testis. Weakly expressed in ovary, small intestine, colon and peripheral blood leukocytes. May be correlative to several tumors, such as ovary serous adenocarcinoma and metastasis mammary gland carcinoma breast.

Similarity:
Belongs to the WD repeat neurobeachin family.
Contains 1 BEACH domain.
Contains 1 BEACH-type PH domain.
Contains 2 WD repeats.

Database links:

Entrez Gene: 65065 Human

Omim: 609816 Human

SwissProt: Q6ZS30 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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